Ellen DeGeneres will end her Emmy-winning daytime talk show after 19 years, the comedian told 'The Hollywood Reporter' in an interview published on Wednesday.
She will discuss the decision on Thursday's show with guest Oprah Winfrey, the entertainment publication said.
"When you’re a creative person, you constantly need to be challenged – and as great as this show is, and as fun as it is, it’s just not a challenge anymore," DeGeneres said in the interview.
The Ellen DeGeneres Show debuted in 2003 and has won more than 60 Emmy awards.
Last year, three top producers exited the show and DeGeneres apologised after reports of a toxic work environment, promising "a new chapter".

Taylor Swift makes VMAs history and dedicates award to Dolly Parton
U2 mark 50 years together with concert at school where it all began
Taylor Swift releases 'Encore' to her hit 'Showgirl' albumĀ
Actors, politicians arrested for protesting against Netanyahu outside UN
Dakota Johnson says thriller 'Verity' puts truth and trust to the test
Katy Perry to headline New Year's Eve Gala at Atlantis