Bahrain will suspend dine-in services at restaurants and cafes and move public and private schools to remote learning for three weeks to contain the spread of the coronavirus, the health ministry said.
It said it had detected a new variant of coronavirus in a number of cases, without specifying which kind.
The new lockdown measures will come into effect on Sunday.
There has been an uptick in coronavirus cases in the Gulf kingdom since December. The country registered 459 new cases on Wednesday, adding to a total of nearly 100,000 since the start of the pandemic, with 370 deaths.
The small island state has the third highest rate of vaccinations per capita in the world so far, according to the Our World in Data website, which is run by an Oxford University research programme.
Bahrain offers its citizens either the Pfizer/BioNTech vaccine or one manufactured by Chinese state-backed pharmaceutical giant Sinopharm free of charge.
The kingdom also approved the AstraZeneca COVID-19 vaccine on Monday for emergency use.
Ukraine's President Volodymyr Zelenskyy called for new strong sanctions against Russia and its allies after Russian drones killed three and injured 31, including six children, in an overnight air attack on Kyiv.
The outlawed Kurdistan Workers Party (PKK) said on Sunday it was withdrawing from Turkey as part of a disarmament process it is coordinating with the government, and pressed Ankara for concrete measures to move the process along.
Israeli forces carried out a "targeted strike" on an individual in central Gaza who was planning to attack Israeli troops, Israel's military said on Saturday.
The leaders of Thailand and Cambodia signed an enhanced ceasefire deal on Sunday in the presence of US President Donald Trump, who intervened in July to bring an end to their deadly five-day border conflict.
Thailand's Queen Mother Sirikit, who brought glamour and elegance to a postwar revival in the country's monarchy and in later years, would occasionally wade into politics, has passed away at the age of 93, the Thai Royal Household Bureau said on Saturday.