Jason Roy and captain Joe Root both smashed centuries as the tourists easily reached their target of 361 with eight balls to spare in Barbados.
It was their highest ever run-chase in the format.
Chris Gayle's innings of 139 off 129 balls went in vain as the Windies' poor form in ODI cricket continued.
The second encounter of the five-match series will be played on Friday.
England forward Kane crowned Ballon d'Or winner, Putellas wins women's award
Harry Kane has completed his long quest for football's highest individual honour on Monday, with the Bayern Munich and England striker winning the Ballon d'Or after a record-breaking season that cemented his status as one of the game's greatest goalscorers.
Mayulu, Godts send PSG top with win over Olympique Lyonnais
Substitutes Senny Mayulu and Mika Godts scored superb second-half goals as Paris St Germain moved to the top of Ligue 1 with a hard-fought 2-0 home win over Olympique Lyonnais on Monday.
Rahimi on target as Al-Ain stay perfect in Asian Champions League
Al-Ain continued their perfect start to the western league phase of the Asian Champions League Elite on Monday with a 2-1 win over Tractor FC from Iran as title holders Al-Ahli secured a late 2-1 victory over 10-man Al-Gharafa.
UAE's new falconry charter honours Sheikh Zayed's legacy
The UAE has unveiled the 'Sheikh Zayed Principles of Falconry' Charter, a new framework to guide the development of falconry and strengthen the country's leadership in the traditional sport.
Entries open as World Triathlon Women's Cup returns to Dubai
Entries are now open for the World Triathlon Women’s Cup Dubai, which makes its way to Al Mamzar Beach Park on December 6, with races for women of all abilities, from first-time triathletes to elite international athletes.
2:00pm - 6:00pm
Brent Black has the biggest stories of the day and the stuff you might have missed.
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