Top seed Karolina Pliskova has crashed out of the US Open following a straight-sets defeat in the second round.
The world no.3 lost 6-1, 7-6 (2) to France’s Caroline Garcia, who will now face 28th seed, American Jennifer Brady.
Elsewhere, sixth seed Petra Kvitova overcame a shaky start to defeat Kateryna Kozlova 7-6 (3), 6-2 in her second-round match, while the 2018 champion, Naomi Osaka, cruised past Camila Giorgi 6-1, 6-2.
In the men’s draw, top seed Novak Djokovic overcame Kyle Edmund 6-7 (7-5), 6-3, 6-4, 6-2 to set up a third-round matchup against No. 28 Jan-Lennard Struff.
Fourth seed Stefanos Tsitsipas also advanced to the third round following a 7-6 (2), 6-3, 6-4 win over wild card Maxime Cressy.


Man City cruise to 4-1 win over Palace
England dismiss Pakistan for 110 to seize control of Lord's test
Raphinha, Fermin score as Barcelona beat Athletic in home opener
Celtic and Rangers to play cup match behind closed doors after pitch invasion
Chelsea and Fulham reach League Cup third round as Welbeck scores on debut